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--> --> Visit Contact JP EN About Message from the Director History Organization Chart Past Directors Archives Publications Outreach BRI VIDEOS Departments Brain Tumor Biology Cellular Neuropathology System Pathology for Neurological Disorders/Tainaka Lab System Pathology for Neurological Disorders/Ueno Lab System Pathology for Neurological Disorders/Laboratory for Evolutionary Brain Pathology Pathology Molecular Pathology (Visiting Professor Program) Neurosurgery Neurology Center for Integrated Human Brain Science Integrated Neuroscience Biological Magnetic Resonance Functional Neurology & Neurosurgery Center for Bioresource-based Researches Molecular Genetics Comparative & Experimental Medicine Animal Model Development Pathology Neuroscience Molecular Neuroscience Neuroscience of Disease/Matsui Lab Neuroscience of Disease/Sugie Lab Endowed Research Branch Advanced Treatment of Neurological Diseases Branch Research Research Findings Research Projects Global Partnerships Young Scientists at BRI Female Scientists at BRI Interview Medical Practice Graduate Degrees Graduate Programs Why study at BRI Student life at BRI Careers after BRI Joint Research Joint Usage / Research Research Equipment & Resources Data & Archives How to Apply for the BRI Global Collaborative Research Events Home> Departments> Neuroscience of Disease -Sugie Lab Brain Science Branch, Center for Bioresource-based ResearchesDepartment of Neuroscience of Disease -Sugie Lab Sugie Lab Website Member Assoc. Prof. Atsushi SUGIE Specially Appointed Assist. Prof. Yohei NITTA Specially Appointed Assist. Prof. Jiro OSAKA Research Focus Neural circuits of the brain usually maintain their function over a long duration; therefore, it is believed that circuit-forming neurons sustain a long-term health-maintenance mechanism via unique cellcell interactions, unlike somatic cells that preserve tissue health via cell turnover. Disruption of this circuit-maintenance mechanism could lead to aging, neurodegenerative diseases, and mental disorders. However, intercellular communication mechanism to maintain neuronal health has not been fully elucidated owing to such an investigation being time consuming. We overcome this complication by taking advantage of the short life cycle and rarely duplicated genes of Drosophila that enable rapid genetic analyses. We are conducting research that focuses on synapses that serve as transmission sites for neuronal information. Further studies are also being undertaken to investigate the metabolism of the phospholipids that constitute the cell membranes between adjacent cells. From these studies, we expect to propose novel findings on the molecular basis of neuroprotection through regulation of synapse transmission and lipid metabolism. About Departments Research Medical Practice Graduate Degrees Joint Research Center Events Visit About This Website Links Sitemap Copyright © 2023 Brain Research Institute, Niigata University. All rights reserved.